Nestled in the picturesque neighborhood of Twin Peaks, this prime mixed-use property offers an exceptional investment opportunity. Comprising a well-maintained building with both residential and commercial units, NC-1 Zoning, it enjoys high visibility on a prominent corner of Portola Drive, a major thoroughfare connecting San Francisco's west and central districts. The property boasts a classic San Francisco aesthetic with a streamlined facade and large, street-facing windows. Units on the ground floor provide excellent exposure to foot and vehicular traffic, while the upper levels feature residential units with abundant natural light and sweeping views of the surrounding hills, Twin Peaks. Onsite parking adds convenience for tenants and customers alike. Located in a highly desirable area, the building benefits from its proximity to neighborhood amenities, including parks, shops, and eateries. It's a short distance from West Portal Village, known for its small-town feel and vibrant commercial district. Glen Canyon Park, with its trails and natural beauty, is just moments away, offering a serene escape in the heart of the city. The property enjoys convenient access to public transportation, including Muni lines, BART, and major freeways, making it a practical choice for commuters. 601-621 Portola Drive is a rare find in one of San Francisco's most livable and connected neighborhoods.