Office Space Available for Lease Immediately. Move-in condition office space. Luxurious office space on the north side of downtown Columbia. Abundant free surface parking (3.39/1,000 SF). Four story office building with atrium lobby, balconies and courtyard. Other amenities located close by. 5457 Twin Knolls Road is situated in the Twin Knolls Business Park, Columbia, Howard County, Maryland 21045. It is adjacent to the Hilton Hotel near the intersection of MD-175 and Little Patuxent Parkway and with a 10 mile radius of Centers for Medicare/Medicaid Services (CMS) and Fort Meade.